2016
91) Design, synthesis and application of an optimized mono-fluorinated aliphatic label for peptide studies by solid-state 19F-NMR
S. O. Kokhan, A. V. Tymtsunik, S. L. Grage, S. Afonin, O. Babii, M. Berditsch, A. V. Strizhak, I. V. Komarov, A. S. Ulrich,* P. K. Mykhailiuk*
Angew. Chem. Int. Ed. 2016, 55, 14788-14792
90) Synthesis of fluoroalkyl pyrazoles from in situ generated C2F5CHN2 and electron-deficient alkenes
P. K. Mykhailiuk,* A. Ishchenko, V. Stepanenko, J. Cossy
Eur. J. Org. Chem. 2016, 33, 5485-5493
89) Expanding synthesizable space of disubstituted 1,2,4-oxadiazoles
A. A. Tolmachev, A. V. Bogolubsky, S. E. Pipko, A. V. Zhemera, A. I. Konovets, O. A. Zaporozhets, P. K. Mykhailiuk,* Y. S. Moroz*
ACS. Comb. Sci. 2016, 18, 616-624
88) Unexpected Reactivity of Trifluoromethyl Diazomethane (CF3CHN2): Electrophilicity of the Terminal N-Atom
A. V. Arkhipov, V. V. Arkhipov, J. Cossy, V. O. Kovtunenko, P. K. Mykhailiuk*
Org. Lett. 2016, 18, 3406-3409
87) 2,2,2-Trifluoroethyl Oxalates in the One-Pot Parallel Synthesis of Hindered Aliphatic Oxamides
A. V. Bogolubsky, Y. S. Moroz,* P. K. Mykhailiuk,* S. E. Pipko, A. I. Konovets, Y. V. Dmytriv, O. A. Zaporozhets, A. Tolmachev
Eur. J. Org. Chem. 2016, 12, 2120-2130
86) Cu-catalyzed O-Difluoromethylation of Functionalized Aliphatic Alcohols: An Access to Complex Molecules with OCF2H group
K. Levchenko, O. P. Datsenko, O. Serhiichuk, A. Tolmachev, V. O.Iaroshenko,* P. K. Mykhailiuk*
J. Org. Chem. 2016, 81, 5803-5813
85) A base promoted multigram synthesis of aminoisoxazoles: valuable building blocks for drug discovery and peptidomimetics
B. Chalyk, I. Kandaurova, K. Hrebeniuk, O. Manoilenko, I. Kulik, R. Iminov, V. Kubyshkin, A. Tverdokhlebov,* O. Ablialimov,* P. K. Mykhailiuk*
RSC Adv. 2016, 6, 25713-25723
84) Synthesis of Functionalized 2-Trifluoromethylquinolines and their Heteroaromatic Analogues
V. V. Khutoryanskiy, A. V. Biitseva, P. K. Mykhailiuk*
Asian J. Org. Chem. 2016, 5, 513-520
83) Lipase kinetic enantiomeric resolution of 1-heteroarylethanols
O. V. Kucher, A. O. Kolodyazhnaya, O. B. Smolii, N. K. Nazarenko, V. Kubyshkin, P. K. Mykhailiuk, A. A. Tolmachev
Tetrahedron Assym. 2016, 27, 341-345
2015
82) Synthesis of Cyclopropyl- and Cyclobutylpiperidines: Advanced Building Blocks for Drug Discovery
I. I. Vyzir, R. T. Iminov, A. Tverdokhlebov,* A. A. Tolmachev, A. V. Shcherbatiuk, P. K. Mykhailiuk,* A. V. Biitseva
Synthesis 2015, 47, 3963-3971
81) 2,2,2-Trifluoroethyl Chlorooxoacetate – Universal Reagent for One-pot Parallel Synthesis of N1-aryl-N2-alkyl-substituted Oxamides
A. V. Bogolubsky, Y. S. Moroz,* P. K. Mykhailiuk,* S. E. Pipko, Y. V. Dmitriv, R. A. Doroschuk, O. A. Zaporozhets, A. Tolmachev
ACS Comb. Sci. 2015, 17, 615-622
80) New Life for Diazoacetonitrile (N2CHCN): in situ Generation and Practical Synthesis of CN-Pyrazoles
P. K. Mykhailiuk*
Eur. J. Org. Chem. 2015, 33, 7235-7239
79) One-Pot Parallel Synthesis of Alkyl Sulfides, Sulfoxides, and Sulfones
A. V. Bogolubsky, Y. S. Moroz,* P. K. Mykhailiuk,* E. N. Ostapchuk, A. V. Rudnichenko, Y. V. Dmytriv, A. N. Bondar, O. A. Zaporozhets, S. E. Pipko, R. A. Doroschuk, L. N. Babichenko, A. I. Konovets, A. Tolmachev
ACS Comb. Sci. 2015, 17, 348–354
78) Synthesis and studies on gem-fluorinated 2-azabicyclo[n.1.0]alkanes
V. Kubyshkin,* Y. Kheylik, P. K. Mykhailiuk*
J. Fluorine Chem. 2015, 175, 73-83
77) Design, Synthesis, and Characterization of SO2-Containing Azabicyclo[3.n.1]alkanes: Promising Building Blocks for Drug Discovery
T. Druzhenko, O. Denisenko, Y. Kheylik, S. Zozulya, S. S. Shishkina, A. Tolmachev, P. K. Mykhailiuk*
Org. Lett. 2015, 17, 1922-1925
76) In Situ Generation of Difluoromethyl Diazomethane for [3+2] Cycloadditions with Alkynes
P. K. Mykhailiuk*
Angew. Chem. Int. Ed. 2015, 22, 6558–6561
75) γ-(S)-Trifluoromethyl proline: Evaluation as a structural substitute of proline for solid state 19F-NMR peptide studies
V. S. Kubyshkin, S. Afonin, S. Kara, N. Budisa, P. K. Mykhailiuk,* A. S. Ulrich*
Org. Biomol. Chem. 2015, 13, 3171-3181
74) Three-component synthesis of fluorinated pyrazoles from fluoroalkylamines, NaNO2 and electron-deficient alkynes
P. K. Mykhailiuk*
Org. Biomol. Chem. 2015, 13, 3438-3445
highlighted in SynFacts
73) Three-component synthesis of C2F5-substituted pyrazoles from C2F5CH2NH2·HCl, NaNO2 and electron-deficient alkynes
P. K. Mykhailiuk*
Beilstein J. Org. Chem. 2015, 11, 16-24
highlighted in SynFacts
72) Facile one-pot synthesis of 4-substituted semicarbazides
A. V. Bogolubsky, Y. S. Moroz,* P. K. Mykhailiuk,* Y. V. Dmytriv, S. E. Pipko, L. N. Babichenko, A. I. Konovets, A. Tolmachev
RSC Adv. 2015, 5, 1063-1069
71) Design and Synthesis of Novel 19F-Amino Acid: A Promising 19F NMR Label for Peptide Studies
D. Bandak, O. Babii, R. Vasiuta, I. V. Komarov, P. K. Mykhailiuk*
Org. Lett. 2015, 17, 226-229
70) Synthesis of isomeric (3,3,3-trifluoropropyl)anilines
S. Trofymchuk, A. Bezdudny, Y. Pustovit,* P. K. Mykhailiuk*
J. Fluorine Chem. 2015, 15, 171-174
69) Multigram Synthesis of Fluoroalkyl-Substituted Pyrazole-4-carboxylic Acids
R. T. Iminov, A. V. Mashkov, I. I. Vyzir, B. A. Chalyk, A. V. Tverdokhlebov,* P. K. Mykhailiuk,* A. A. Tolmachev, Y. M. Volovenko, A. Biitseva
Eur. J. Org. Chem. 2015, 4, 886-891
2014
68) Enzyme-Catalyzed Kinetic Resolution of 2,2,2-Trifluoro-1-(heteroaryl)ethanols: Experimental and Docking Studies
O. V. Kucher, A. O. Kolodiazhnaya, O. B. Smolii, D. V. Prisuazhnyk, K. A. Tolmacheva, Y. S. Moroz,* P. K. Mykhailiuk,* A. A. Tolmachev
Eur. J. Org. Chem. 2014, 7692-7698
67) A One-Pot Parallel Reductive Amination of Aldehydes with 2-Heteroaromatic
A. V. Bogolubsky, Y. S. Moroz,* P. K. Mykhailiuk,* D. M. Panov, E. Pipko, A. I. Konovets, A. Tolmachev
ACS Comb. Sci. 2014, 16, 375-380
66) Bis(2,2,2-trifluoroethyl) Carbonate as a Condensing Agent in One-Pot Parallel Synthesis of Unsymmetrical Aliphatic Ureas
A. V. Bogolubsky, Y. S. Moroz,* P. K. Mykhailiuk,* D. S. Granat, E. Pipko, A. I. Konovets, R. Doroschuk, A. Tolmachev
ACS Comb. Sci. 2014, 16, 303-308
65) Structure Analysis and Conformational Transitions of the Cell Penetrating Peptide Transportan 10 in the Membrane-Bound State
S. Fanghaenel, P. Wadhwani, E. Strandberg, W. P. R. Verdurmen, J. Buerck, S. Ehni, P. K. Mykhailiuk, S. Afonin, I. V. Komarov, R. Brock, A. S. Ulrich
PLOS ONE 2014, 9, e99653
64) In situ-generation of C2F5CHN2 and its first reaction – [3+2]-cycloaddition with alkenes
P. K. Mykhailiuk*
Chem. Eur. J. 2014, 17, 4942-4947
63) One-pot synthesis of CF3-substituted pyrazolines / pyrazoles from electron-deficient alkenes / alkynes and in situ generated CF3CHN2. Optimized synthesis of tris-trifluoromethylpyrazole
E. Y. Slobodyanyuk, O. S. Artamonov, O. V. Shishkin, P. K. Mykhailiuk*
Eur. J. Org. Chem. 2014, 2487-2495
62) Synthesis of trifluoromethyl-substituted 3 azabicyclo[n.1.0]alkanes: advanced building blocks for drug discovery
O. S. Artamonov, E. Y. Slobodyanyuk, D. M. Volochnyuk, I. V. Komarov, A. A. Tolmachev, P. K. Mykhailiuk*
Eur. J. Org. Chem. 2014, 3592-3599
61) Design and synthesis of a monofluoro-substituted aromatic amino acid as a conformationally restricted 19F-NMR label for membrane-bound peptides
A. N. Tkachenko, P. K. Mykhailiuk,* D. S. Radchenko, Oleg Babii, S. Afonin, A. S. Ulrich,* I. V. Komarov
Eur. J. Org. Chem. 2014, 3584-3591
60) Sulfonyl fluorides as alternative to sulfonyl chlorides in parallel synthesis of aliphatic sulfonamides
A. V. Bogolubsky, Y. S. Moroz,* P. K. Mykhailiuk,* S. E. Pipko, A. I. Konovets, I. V. Sadkova, A. Tolmachev
ACS Comb. Sci. 2014, 16, 192-197
59) Enzymatic resolution of chroman-4-ol and its core analogues with Burkholderia cepacia lipase
O. V. Kucher, A. O. Kolodyazhnaya, O. B. Smolii, A. I. Boiko, V. S. Kubyshkin, P. K. Mykhailiuk, A. A. Tolmachev
Tetrahedron Assym. 2014, 25, 563-567
58) Controlling Biological Activity with Light: Diarylethene-Containing Cyclic Peptidomimetics
O. Babii, S. Afonin, M. Berditsch, S. Reiβer, P. K. Mykhailiuk, V. S. Kubyshkin, T. Steinbrecher, A. S. Ulrich, I. V. Komarov
Angew. Chem. Int. Ed. 2014, 53, 3392-3395
57) Convenient synthesis of enantiopure (R-) and (S-)-3-fluoro-3-aminomethylpyrrolidines
V. S. Yarmolchuk, V. L. Mykhalchuk, P. K. Mykhailiuk*
Tetrahedron 2014, 70, 3011-3017
56) Synthesis and functionalization of 3-azolyl-quinoxalin-2-ones
O. V. Geraschenko,* P. V. Khodakovskiy, O. V. Shishkin, A. A. Tolmachev, P. K. Mykhailiuk*
Synthesis 2014, 46, 1487-1492
55) Direct non-catalytic electrophilic trifluoroacetylation of electron-rich pyrazoles
V. Yarmoliuk, V. V. Arhipov, M. V. Stambirskyi, Y. V. Dmytriv, O. V. Shishkin, A. A. Tolmachev, P. K. Mykhailiuk*
Synthesis 2014, 46, 1254-1260
Comments are closed.